You will show me the path of life; In Your presence is fullness of joy; At Your right hand are pleasures forevermore.
(Psalm 16:11)

Prayer is the only doorway to a living fellowship with the presence and power of the Father God Almighty and the Lord Jesus Christ.  There is no other way to stand before the throne room of God Almighty.

Ask, and it will be given to you; seek, and you will find; knock, and it will be opened to you. For everyone who asks receives, and he who seeks finds, and to him who knocks it will be opened.
(Matthew 7:7-8)

You were created to fellowship with the Lord Jesus Christ continually.  The cares and persecutions of this life were sent to distract you and to take your eyes and heart off of the power and presence of the Lord Jesus Christ.  When that happens you have left His fellowship of love, power and peace.

A prayer filled life is a life filled in constant fellowship with the Lord Jesus Christ.

I have told you these things, so that in Me you may have [perfect] peace and confidence. In the world you have tribulation and trials and distress and frustration; but be of good cheer [take courage; be confident, certain, undaunted]! For I have overcome the world. [I have deprived it of power to harm you and have conquered it for you.
(John 16:33, Amplified Bible)

The greatest joy, love and peace you will ever know in this life, is when you are in His presence in prayer.  You can live continually in His presence and power with a life filled with prayer and fellowship by keeping your eyes and heart on Him regardless of the circumstances.

that which we have seen and heard we declare to you, that you also may have fellowship with us; and truly our fellowship is with the Father and with His Son Jesus Christ.
(1 John 1:3)
Let us therefore come boldly to the throne of grace, that we may obtain mercy and find grace to help in time of need.
(Hebrews 4:16)
He who believes in Me, as the Scripture has said, out of his heart will flow rivers of living water.
(John 7:38)